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Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
BACKGROUND: Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. The relationships between patterns of mutations and epigenetic phenotypes are not yet clear. METHODS: We analyzed the genomes of 200 clinically annotated adult cases of de novo AML, using ei...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767041/ https://ncbi.nlm.nih.gov/pubmed/23634996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1301689 |
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