Thioredoxin Ameliorates Cutaneous Inflammation by Regulating the Epithelial Production and Release of Pro-Inflammatory Cytokines

Human thioredoxin-1 (TRX) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys-. It has been demonstrated that systemic administration and transgenic overexpression of TRX ameliorate inflammation in various animal models, but its anti-inflammatory mechanism is not well c...

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Bibliographic Details
Main Authors: Tian, Hai, Matsuo, Yoshiyuki, Fukunaga, Atsushi, Ono, Ryusuke, Nishigori, Chikako, Yodoi, Junji
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766902/
https://ncbi.nlm.nih.gov/pubmed/24058364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00269
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