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Censoring of self-reactive B cells by follicular dendritic cell-displayed self-antigen

In the secondary lymphoid organs, intimate contact with follicular dendritic cells (FDCs) is required for B cell retention and antigen-driven selection during the germinal center response. However, selection of self-reactive B cells by antigen on FDCs has not been addressed. To this end, we generate...

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Autores principales: Yau, Irene W., Cato, Matthew H., Jellusova, Julia, Hurtado de Mendoza, Tatiana, Brink, Robert, Rickert, Robert C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766769/
https://ncbi.nlm.nih.gov/pubmed/23817432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201569
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