Development and validation of LC-MS/MS method for determination of very long acyl chain (C22:0 and C24:0) ceramides in human plasma

Ceramide is a key metabolite in both anabolic and catabolic pathways of sphingolipids. The very long fatty acyl chain ceramides N-(docosanoyl)-sphing-4-enine (Cer(22:0)) and N-(tetracosanoyl)-sphing-4-enine (Cer(24:0)) are associated with multiple biological functions. Elevated levels of these sphin...

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Bibliografiske detaljer
Main Authors: Jiang, Hui, Hsu, Fong-Fu, Farmer, Marsha S., Peterson, Linda R., Schaffer, Jean E., Ory, Daniel S., Jiang, Xuntian
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766747/
https://ncbi.nlm.nih.gov/pubmed/23857140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-013-7166-9
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