Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein

Glutathione S-transferase (GST) is the key enzyme in multidrug resistance (MDR) of tumour. Inhibition of the expression or activity of GST has emerged as a promising therapeutic strategy for the reversal of MDR. Coniferyl ferulate (CF), isolated from the root of Angelica sinensis (Oliv.) Diels (Radi...

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Detalhes bibliográficos
Main Authors: Chen, Chang, Wu, Chuanhong, Lu, Xinhua, Yan, Zhiyong, Gao, Jian, Zhao, Hui, Li, Shaojing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766616/
https://ncbi.nlm.nih.gov/pubmed/24058374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/639083
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