Rapid Purification and Procoagulant and Platelet Aggregating Activities of Rhombeobin: A Thrombin-Like/Gyroxin-Like Enzyme from Lachesis muta rhombeata Snake Venom

We report a rapid purification method using one-step chromatography of SVSP Rhombeobin (LMR-47) from Lachesis muta rhombeata venom and its procoagulant activities and effects on platelet aggregation. The venom was fractionated by a single chromatographic step in RP-HPLC on a C8 Discovery BIO Wide Po...

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Autors principals: Torres-Huaco, Frank Denis, Werneck, Cláudio C., Vicente, Cristina Pontes, Vassequi-Silva, Talita, Nery-Diez, Ana Cláudia Coelho, Mendes, Camila B., Antunes, Edson, Marangoni, Sérgio, Damico, Daniela C. S.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766598/
https://ncbi.nlm.nih.gov/pubmed/24058917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/903292
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