Pharmacological Characterization of Membrane-Expressed Human Trace Amine-Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer cAMP Biosensor

Trace amines are neurotransmitters whose role in regulating invertebrate physiology has been appreciated for many decades. Recent studies indicate that trace amines may also play a role in mammalian physiology by binding to a novel family of G protein-coupled receptors (GPCRs) that are found through...

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Main Authors: Barak, Larry S., Salahpour, Ali, Zhang, Xiaodong, Masri, Bernard, Sotnikova, Tatyana D., Ramsey, Amy J., Violin, Jonathan D., Lefkowitz, Robert J., Caron, Marc G., Gainetdinov, Raul R.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766527/
https://ncbi.nlm.nih.gov/pubmed/18524885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.048884
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