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APOE ε4, Alzheimer’s disease pathology, cerebrovascular disease, and cognitive change over the years prior to death

BACKGROUND: Much remains to be learned about the effect of the APOE ε4 allele on the trajectory of cognitive aging including the onset of terminal decline and rates of decline before and after, particularly in the presence of Alzheimer’s disease (AD) brain pathology. OBJECTIVE: To examine the associ...

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Hlavní autoři: Yu, Lei, Boyle, Patricia, Schneider, Julie A., Segawa, Eisuke, Wilson, Robert S., Leurgans, Sue, Bennett, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766432/
https://ncbi.nlm.nih.gov/pubmed/23647000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/a0031642
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