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The utility of ionotropic glutamate receptor antagonists in the treatment of nociception induced by epidural glutamate infusion in rats

BACKGROUND: The authors have previously demonstrated that human herniated disc material contains high concentrations of free glutamate. In an experimental model, elevated epidural glutamate concentrations in the lumbar spine can cause a focal hyperesthetic state. METHODS: Rats underwent epidural glu...

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Detalhes bibliográficos
Main Authors: Osgood, Doreen P., Harrington, William F., Kenney, Elizabeth V., Harrington, J. Frederick
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766326/
https://ncbi.nlm.nih.gov/pubmed/24032081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2152-7806.116791
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