Identification of a novel infection-enhancing epitope on dengue prM using a dengue cross-reacting monoclonal antibody

BACKGROUND: Dengue virus (DENV) infection is the most important arthropod- borne viral disease in human, but antiviral therapy and approved vaccines remain unavailable due to antibody-dependent enhancement (ADE) phenomenon. Many studies showed that pre-membrane (prM)-specific antibodies do not effic...

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Hlavní autoři: Luo, Ya-Yan, Feng, Jun-Jie, Zhou, Jun-Mei, Yu, Zhi-Zhun, Fang, Dan-Yun, Yan, Hui-Jun, Zeng, Gu-Cheng, Jiang, Li-Fang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765915/
https://ncbi.nlm.nih.gov/pubmed/23987307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-13-194
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