The effects of statins on the mevalonic acid pathway in recombinant yeast strains expressing human HMG-CoA reductase

BACKGROUND: The yeast Saccharomyces cerevisiae can be a useful model for studying cellular mechanisms related to sterol synthesis in humans due to the high similarity of the mevalonate pathway between these organisms. This metabolic pathway plays a key role in multiple cellular processes by synthesi...

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Detalhes bibliográficos
Main Authors: Maciejak, Agata, Leszczynska, Agata, Warchol, Ilona, Gora, Monika, Kaminska, Joanna, Plochocka, Danuta, Wysocka-Kapcinska, Monika, Tulacz, Dorota, Siedlecka, Joanna, Swiezewska, Ewa, Sojka, Maciej, Danikiewicz, Witold, Odolczyk, Norbert, Szkopinska, Anna, Sygitowicz, Grazyna, Burzynska, Beata
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765880/
https://ncbi.nlm.nih.gov/pubmed/24128347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-68
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