Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II interferons

BACKGROUND: The carcinoembryonic antigen (CEA)-related cell adhesion molecules CEACAM1 (BGP, CD66a), CEACAM5 (CEA, CD66e) and CEACAM6 (NCA, CD66c) are expressed in human lung. They play a role in innate and adaptive immunity and are targets for various bacterial and viral adhesins. Two pathogens tha...

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Main Authors: Klaile, Esther, Klassert, Tilman E, Scheffrahn, Inka, Müller, Mario M, Heinrich, Annina, Heyl, Kerstin A, Dienemann, Hendrik, Grünewald, Christiane, Bals, Robert, Singer, Bernhard B, Slevogt, Hortense
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765474/
https://ncbi.nlm.nih.gov/pubmed/23941132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-85
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