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Germline deletions in the EPCAM gene as a cause of Lynch syndrome – literature review
Lynch syndrome (clinically referred to as HNPCC – Hereditary Non-Polyposis Colorectal Cancer) is a frequent, autosomal, dominantly-inherited cancer predisposition syndrome caused by various germline alterations that affect DNA mismatch repair genes, mainly MLH1 and MSH2. Patients inheriting this pre...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3765447/ https://ncbi.nlm.nih.gov/pubmed/23938213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-11-9 |
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