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Higher BMP/Smad sensitivity of tendon-derived stem cells (TDSCs) isolated from the collagenase-induced tendon injury model: possible mechanism for their altered fate in vitro

BACKGROUND: Ectopic expression of BMP-2, BMP-4 and BMP-7 was observed in clinical samples of tendinopathy and collagenase-induced (CI) tendon injury rat model. TDSCs isolated from the CI model showed increased non-tenogenic differentiation potential and hence altered fate compared to the TDSCs isola...

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Hlavní autoři: Lui, Pauline Po Yee, Wong, Yin Mei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765363/
https://ncbi.nlm.nih.gov/pubmed/23964681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-14-248
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