Lipopolysaccharide-Induced Weakness in the Preterm Diaphragm Is Associated with Mitochondrial Electron Transport Chain Dysfunction and Oxidative Stress

Diaphragmatic contractility is reduced in preterm lambs after lipopolysaccharide (LPS) exposure in utero. The mechanism of impaired fetal diaphragm contractility after LPS exposure is unknown. We hypothesise that in utero exposure to LPS induces a deficiency of mitochondrial complex activity and oxi...

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Autors principals: Song, Yong, Pinniger, Gavin J., Bakker, Anthony J., Moss, Timothy J. M., Noble, Peter B., Berry, Clare A., Pillow, Jane J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765262/
https://ncbi.nlm.nih.gov/pubmed/24039949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073457
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