Fc-gamma receptor polymorphisms as predictive and prognostic factors in patients receiving oncolytic adenovirus treatment

BACKGROUND: Oncolytic viruses have shown potential as cancer therapeutics, but not all patients seem to benefit from therapy. Polymorphisms in Fc gamma receptors (FcgRs) lead to altered binding affinity of IgG between the receptor allotypes and therefore contribute to differences in immune defense m...

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Библиографические подробности
Главные авторы: Hirvinen, Mari, Heiskanen, Raita, Oksanen, Minna, Pesonen, Saila, Liikanen, Ilkka, Joensuu, Timo, Kanerva, Anna, Cerullo, Vincenzo, Hemminki, Akseli
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765225/
https://ncbi.nlm.nih.gov/pubmed/23965133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-193
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