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Fc-gamma receptor polymorphisms as predictive and prognostic factors in patients receiving oncolytic adenovirus treatment

BACKGROUND: Oncolytic viruses have shown potential as cancer therapeutics, but not all patients seem to benefit from therapy. Polymorphisms in Fc gamma receptors (FcgRs) lead to altered binding affinity of IgG between the receptor allotypes and therefore contribute to differences in immune defense m...

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Detalhes bibliográficos
Main Authors: Hirvinen, Mari, Heiskanen, Raita, Oksanen, Minna, Pesonen, Saila, Liikanen, Ilkka, Joensuu, Timo, Kanerva, Anna, Cerullo, Vincenzo, Hemminki, Akseli
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765225/
https://ncbi.nlm.nih.gov/pubmed/23965133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-193
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