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Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling

Megakaryocytes generate platelets through extensive reorganization of the cytoskeleton and plasma membrane. Cdc42 interacting protein 4 (CIP4) is an F-BAR protein that localizes to membrane phospholipids through its BAR domain and interacts with Wiskott-Aldrich Syndrome Protein (WASP) via its SRC ho...

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書誌詳細
主要な著者: Chen, Yolande, Aardema, Jorie, Kale, Sayali, Whichard, Zakary L., Awomolo, Arinola, Blanchard, Elisabeth, Chang, Brian, Myers, David R., Ju, Lining, Tran, Reginald, Reece, David, Christensen, Hilary, Boukour, Siham, Debili, Najet, Strom, Ted S., Rawlings, David, Vázquez, Francisco X., Voth, Gregory A., Zhu, Cheng, Kahr, Walter H. A., Lam, Wilbur A., Corey, Seth J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765055/
https://ncbi.nlm.nih.gov/pubmed/23881916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-484550
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