Polyunsaturated fatty acids affect the localization and signaling of PIP3/AKT in prostate cancer cells

AKT is a serine–threonine protein kinase that plays important roles in cell growth, proliferation and apoptosis. It is activated after binding to phosphatidylinositol phosphates (PIPs) with phosphate groups at positions 3,4 and 3,4,5 on the inositol ring. In spite of extensive research on AKT, one a...

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Autors principals: Gu, Zhennan, Wu, Jiansheng, Wang, Shihua, Suburu, Janel, Chen, Haiqin, Thomas, Michael J., Shi, Lihong, Edwards, Iris J., Berquin, Isabelle M., Chen, Yong Q.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Original Manuscript
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765042/
https://ncbi.nlm.nih.gov/pubmed/23633519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt147
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