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Multivalency Amplifies the Selection and Affinity of Bradykinin-Derived Peptide for Lipid Nanovesicles
The trimer of a Bradykinin derivative displayed more than five-fold increase in binding affinity for phosphatidylserine-enriched nanovesicles as compared to its monomeric precursor. The nanovesicle selection is directly correlated to multivalency, which amplified the electrostatic attraction. This s...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3764994/ https://ncbi.nlm.nih.gov/pubmed/23715428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mb70109c |
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