Metastasis Suppressor Tetraspanin CD82/KAI1 Regulates Ubiquitylation of Epidermal Growth Factor Receptor

Ligand-induced ubiquitylation of EGF receptor (EGFR) is an important regulatory mechanism that controls endocytic trafficking of the receptor and its signaling potential. Here we report that tetraspanin CD82/KAI1 specifically suppresses ubiquitylation of EGFR after stimulation with heparin-binding E...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Odintsova, Elena, van Niel, Guillaume, Conjeaud, Hélène, Raposo, Graça, Iwamoto, Ryo, Mekada, Eisuke, Berditchevski, Fedor
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764837/
https://ncbi.nlm.nih.gov/pubmed/23897813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.439380
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