Constitutive Activation of Signal Transducer and Activator of Transcription 3 (STAT3) and Nuclear Factor κB Signaling in Glioblastoma Cancer Stem Cells Regulates the Notch Pathway

Malignant gliomas are locally aggressive, highly vascular tumors that have a dismal prognosis, and present therapies provide little improvement in the disease course and outcome. Many types of malignancies, including glioblastoma, originate from a population of cancer stem cells (CSCs) that are able...

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Detalhes bibliográficos
Main Authors: Garner, Jo Meagan, Fan, Meiyun, Yang, Chuan He, Du, Ziyun, Sims, Michelle, Davidoff, Andrew M., Pfeffer, Lawrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764819/
https://ncbi.nlm.nih.gov/pubmed/23902772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.477950
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