Burst activity and ultrafast activation kinetics of Ca(V)1.3 Ca(2+) channels support presynaptic activity in adult gerbil hair cell ribbon synapses

Auditory information transfer to afferent neurons relies on precise triggering of neurotransmitter release at the inner hair cell (IHC) ribbon synapses by Ca(2+) entry through Ca(V)1.3 Ca(2+) channels. Despite the crucial role of Ca(V)1.3 Ca(2+) channels in governing synaptic vesicle fusion, their e...

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Autori principali: Zampini, Valeria, Johnson, Stuart L, Franz, Christoph, Knipper, Marlies, Holley, Matthew C, Magistretti, Jacopo, Masetto, Sergio, Marcotti, Walter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
Soggetti:
Neuroscience: Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764630/
https://ncbi.nlm.nih.gov/pubmed/23713031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.251272
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