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SIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress

SIRT1 is a NAD(+)-dependent protein deacetylase that has a very large number of established protein substrates and an equally impressive list of biological functions thought to be regulated by its activity. Perhaps as notable is the remarkable number of points of conflict concerning the role of SIRT...

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Bibliographic Details
Main Authors: McBurney, Michael W., Clark-Knowles, Katherine V., Caron, Annabelle Z., Gray, Douglas A.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764470/
https://ncbi.nlm.nih.gov/pubmed/24020004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912474893
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