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Involvement of A20 in the molecular switch that activates the non-canonical NF-кB pathway
The non-canonical NF-κB pathway is crucial for the immune system. A critical event in activation of the non-canonical pathway is the attenuation of NF-κB-inducing kinase (NIK) degradation, which is promoted by continuous polyubiquitination of NIK catalyzed by the NIK ubiquitin-ligase complex compose...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3764444/ https://ncbi.nlm.nih.gov/pubmed/24008839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02568 |
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