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Involvement of A20 in the molecular switch that activates the non-canonical NF-кB pathway

The non-canonical NF-κB pathway is crucial for the immune system. A critical event in activation of the non-canonical pathway is the attenuation of NF-κB-inducing kinase (NIK) degradation, which is promoted by continuous polyubiquitination of NIK catalyzed by the NIK ubiquitin-ligase complex compose...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yamaguchi, Noritaka, Oyama, Masaaki, Kozuka-Hata, Hiroko, Inoue, Jun-ichiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764444/
https://ncbi.nlm.nih.gov/pubmed/24008839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02568
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