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Reversal of the Antimicrobial Activity of Trimethoprim by Thymidine in Commercially Prepared Media

The ability of a potent dihydrofolate reductase inhibitor, trimethoprim, to inhibit the growth of Escherichia coli B in vitro is dependent on the composition of the medium in which the cells are grown. The inhibition observed in minimal broth could be partially reversed by the addition of thymidine,...

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Detalhes bibliográficos
Main Authors: Koch, Audrey E., Burchall, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC376424/
https://ncbi.nlm.nih.gov/pubmed/4943586
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