Suppression of Virus Specific Immune Responses by IL-10 in Acute Dengue Infection

BACKGROUND: Elevated IL-10 has been shown to be associated with severe dengue infection (DI). We proceeded to investigate the role of IL-10 in the pathogenesis of acute DI. MATERIALS AND METHODS: Ex vivo and cultured IFNγ ELISpot assays for dengue virus (DENV) NS3 protein and non dengue viral protei...

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Main Authors: Malavige, Gathsaurie Neelika, Jeewandara, Chandima, Alles, K. M. Luckmaal, Salimi, Maryam, Gomes, Laksiri, Kamaladasa, Achala, Jayaratne, S. D., Ogg, Graham Stuart
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764236/
https://ncbi.nlm.nih.gov/pubmed/24040431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002409
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