A Comprehensive Analysis of In Vitro and In Vivo Genetic Fitness of Pseudomonas aeruginosa Using High-Throughput Sequencing of Transposon Libraries

High-throughput sequencing of transposon (Tn) libraries created within entire genomes identifies and quantifies the contribution of individual genes and operons to the fitness of organisms in different environments. We used insertion-sequencing (INSeq) to analyze the contribution to fitness of all n...

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Autori principali: Skurnik, David, Roux, Damien, Aschard, Hugues, Cattoir, Vincent, Yoder-Himes, Deborah, Lory, Stephen, Pier, Gerald B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764216/
https://ncbi.nlm.nih.gov/pubmed/24039572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003582
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