Inhibition of Type I Insulin-Like Growth Factor Receptor Signaling Attenuates the Development of Breast Cancer Brain Metastasis

Brain metastasis is a common cause of mortality in cancer patients, yet potential therapeutic targets remain largely unknown. The type I insulin-like growth factor receptor (IGF-IR) is known to play a role in the progression of breast cancer and is currently being investigated in the clinical settin...

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Detalhes bibliográficos
Main Authors: Saldana, Sandra M., Lee, Heng-Huan, Lowery, Frank J., Khotskaya, Yekaterina B., Xia, Weiya, Zhang, Chenyu, Chang, Shih-Shin, Chou, Chao-Kai, Steeg, Patricia S., Yu, Dihua, Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764163/
https://ncbi.nlm.nih.gov/pubmed/24039934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073406
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