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HDAC1 and HDAC2 Restrain the Intestinal Inflammatory Response by Regulating Intestinal Epithelial Cell Differentiation

Acetylation and deacetylation of histones and other proteins depends on histone acetyltransferases and histone deacetylases (HDACs) activities, leading to either positive or negative gene expression. HDAC inhibitors have uncovered a role for HDACs in proliferation, apoptosis and inflammation. Howeve...

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Detalhes bibliográficos
Main Authors: Turgeon, Naomie, Blais, Mylène, Gagné, Julie-Moore, Tardif, Véronique, Boudreau, François, Perreault, Nathalie, Asselin, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764035/
https://ncbi.nlm.nih.gov/pubmed/24040068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073785
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