Selected Approaches for Rational Drug Design and High Throughput Screening to Identify Anti-Cancer Molecules

Structure-based modeling combined with rational drug design, and high throughput screening approaches offer significant potential for identifying and developing lead compounds with therapeutic potential. The present review focuses on these two approaches using explicit examples based on specific der...

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Main Authors: Hedvat, Michael, Emdad, Luni, Das, Swadesh K., Kim, Keetae, Dasgupta, Santanu, Thomas, Shibu, Hu, Bin, Zhu, Shan, Dash, Rupesh, Quinn, Bridget A., Oyesanya, Regina A., Kegelman, Timothy P., Sokhi, Upneet K., Sarkar, Siddik, Erdogan, Eda, Menezes, Mitchell E., Bhoopathi, Praveen, Wang, Xiang-Yang, Pomper, Martin G., Wei, Jun, Wu, Bainan, Stebbins, John L., Diaz, Paul W., Reed, John C., Pellecchia, Maurizio, Sarkar, Devanand, Fisher, Paul B.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763986/
https://ncbi.nlm.nih.gov/pubmed/22931411
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