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Dendritic Spine Density, Morphology, and Fibrillar Actin Content Surrounding Amyloid-β Plaques in a Mouse Model of Amyloid-β Deposition

Dendritic spines are the site of the majority of excitatory synapses, the loss of which correlates with cognitive impairment in patients with Alzheimer disease. Substantial evidence indicates that amyloid-β (Aβ) peptide, either insoluble fibrillar Aβ deposited into plaques or soluble non-fibrillar A...

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Detalhes bibliográficos
Main Authors: Kirkwood, Caitlin M., Ciuchta, Jennifer, Ikonomovic, Milos D., Fish, Kenneth N., Abrahamson, Eric E., Murray, Patrick S., Klunk, William E., Sweet, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763821/
https://ncbi.nlm.nih.gov/pubmed/23860033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31829ecc89
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