Physical Factors Affecting Plasmid DNA Compaction in Stearylamine-Containing Nanoemulsions Intended for Gene Delivery

Cationic lipids have been used in the development of non-viral gene delivery systems as lipoplexes. Stearylamine, a cationic lipid that presents a primary amine group when in solution, is able to compact genetic material by electrostatic interactions. In dispersed systems such as nanoemulsions this...

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Autors principals: Silva, André Leandro, Júnior, Francisco Alexandrino, Verissimo, Lourena Mafra, Agnez-Lima, Lucymara Fassarella, Egito, Lucila Carmem Monte, de Oliveira, Anselmo Gomes, do Egito, Eryvaldo Socrates Tabosa
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763655/
https://ncbi.nlm.nih.gov/pubmed/24281666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph5060643
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