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Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cells
Oxidized bases in DNA have been implicated in cancer, aging and neurodegenerative disease. We have developed an approach combining single-cell gel electrophoresis (comet) with fluorescence in situ hybridization (FISH) that enables the comparative quantification of low, physiologically relevant level...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763531/ https://ncbi.nlm.nih.gov/pubmed/23775797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt524 |
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