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Decoding in the absence of a codon by tmRNA and SmpB in the ribosome

In bacteria, ribosomes stalled at the end of truncated messages are rescued by tmRNA, a bifunctional molecule that acts as both a tRNA and mRNA, and SmpB, a small protein that works in concert with tmRNA. Here we present the crystal structure at 3.2 Å resolution of a tmRNA fragment, SmpB and elongat...

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Detalles Bibliográficos
Main Authors: Neubauer, Cajetan, Gillet, Reynald, Kelley, Ann C., Ramakrishnan, V.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763467/
https://ncbi.nlm.nih.gov/pubmed/22422985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1217039
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