GluR6-FasL-Trx2 mediates denitrosylation and activation of procaspase-3 in cerebral ischemia/reperfusion in rats

Global cerebral ischemia/reperfusion (I/R) facilitates the activation of procaspase-3 and promotes apoptosis in hippocampus. But the mechanisms have remained uncharacterized. Protein S-nitrosylation and denitrosylation is an important reversible posttranslational modification, which is a common mech...

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Bibliografiske detaljer
Main Authors: Sun, N, Hao, J-R, Li, X-Y, Yin, X-H, Zong, Y-Y, Zhang, G-Y, Gao, C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763460/
https://ncbi.nlm.nih.gov/pubmed/23949220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.299
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