Selective GPER activation decreases proliferation and activates apoptosis in tumor Leydig cells

We have previously shown that estrogens binding to estrogen receptor (ER) α increase proliferation of Leydig tumor cells. Estrogens can also bind to G protein-coupled ER (GPER) and activation of this receptor can either increase or decrease cell proliferation of several tumor types. The aim of this...

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Detalles Bibliográficos
Main Authors: Chimento, A, Casaburi, I, Bartucci, M, Patrizii, M, Dattilo, R, Avena, P, Andò, S, Pezzi, V, Sirianni, R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763437/
https://ncbi.nlm.nih.gov/pubmed/23907461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.275
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