HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

Histone deacetylase inhibitors (HDACIs) interfere with the epigenetic process of histone acetylation and are known to have analgesic properties in models of chronic inflammatory pain. The aim of this study was to determine whether these compounds could also affect neuropathic pain. Different class I...

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Autors principals: Denk, Franziska, Huang, Wenlong, Sidders, Ben, Bithell, Angela, Crow, Megan, Grist, John, Sharma, Simone, Ziemek, Daniel, Rice, Andrew S.C., Buckley, Noel J., McMahon, Stephen B.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763368/
https://ncbi.nlm.nih.gov/pubmed/23693161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.05.021
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