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Large-Scale Purification of Rubella Virus and Preparation of an Experimental Split Rubella Virus Vaccine

Large-scale purification of rubella virus from tissue culture fluid and preparation of an experimental rubella subunit vaccine are described. The virus, purified isopycnically in sucrose gradients, was Tween 80-ether treated, and the product was filtered sterile. The vaccines were of two types, form...

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Detalhes bibliográficos
Publicado no:Appl Microbiol
Main Authors: Väänänen, Pertti, Vaheri, Antti
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC376293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5119198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/am.22.3.255-259.1971
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