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Impact of Viral Factors on Subcellular Distribution and RNA Export Activity of HIV-1 Rev in Astrocytes 1321N1

CNS associated cells are permissive to HIV-1 infection, but poor in virus production due to attenuated Rev activity. The temporal and the spatial distribution of Rev in human astrocyte 1321N1 and glioblastoma GO-G-CCM were monitored for explaining the reduced Rev activity and low viral production du...

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Détails bibliographiques
Auteurs principaux: Banerjee, Atoshi, Benjamin, Ronald, Banerjee, Sharmistha
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762830/
https://ncbi.nlm.nih.gov/pubmed/24023789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072905
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