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The HIV-1 Nef Protein Binds Argonaute-2 and Functions as a Viral Suppressor of RNA Interference

The HIV-1 accessory protein Nef is an important virulence factor. It associates with cellular membranes and modulates the endocytic machinery and signaling pathways. Nef also increases the proliferation of multivesicular bodies (MVBs), which are sites for virus assembly and budding in macrophages. T...

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Détails bibliographiques
Auteurs principaux: Aqil, Madeeha, Naqvi, Afsar Raza, Bano, Aalia Shahr, Jameel, Shahid
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762824/
https://ncbi.nlm.nih.gov/pubmed/24023945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074472
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