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Switching on RNA Silencing Suppressor Activity by Restoring Argonaute Binding to a Viral Protein

We found that Sweet potato feathery mottle virus (SPFMV) P1, a close homologue of Sweet potato mild mottle virus P1, did not have any silencing suppressor activity. Remodeling the Argonaute (AGO) binding domain of SPFMV P1 by the introduction of two additional WG/GW motifs converted it to a silencin...

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Autori principali: Szabó, Edit Z., Manczinger, Máté, Göblös, Anikó, Kemény, Lajos, Lakatos, Lóránt
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421681/
https://ncbi.nlm.nih.gov/pubmed/22623784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00627-12
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