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Lrig2-Deficient Mice Are Protected against PDGFB-Induced Glioma

BACKGROUND: The leucine-rich repeats and immunoglobulin-like domains (LRIG) proteins constitute an integral membrane protein family that has three members: LRIG1, LRIG2, and LRIG3. LRIG1 negatively regulates growth factor signaling, but little is known regarding the functions of LRIG2 and LRIG3. In...

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Detalhes bibliográficos
Main Authors: Rondahl, Veronica, Holmlund, Camilla, Karlsson, Terese, Wang, Baofeng, Faraz, Mahmood, Henriksson, Roger, Hedman, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762791/
https://ncbi.nlm.nih.gov/pubmed/24023893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073635
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