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MicroRNA-205 downregulates mixed-lineage-AF4 oncogene expression in acute lymphoblastic leukemia

Myeloid/lymphoid or mixed-lineage AF4 acute lymphoblastic leukemia (MLL-AF4 ALL) is a pediatric leukemia that occurs rarely in adults. MLL-AF4 ALL is typically characterized by the presence of chromosomal translocation (t(4;1l)(q21;q23)), leading to expression of MLL-AF4 fusion protein. Although MLL...

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Autors principals: Dou, Liping, Li, Jingxin, Zheng, Dehua, Li, Yonghui, Gao, Xiaoning, Xu, Chengwang, Gao, Li, Wang, Lili, Yu, Li
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762764/
https://ncbi.nlm.nih.gov/pubmed/24009426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S45376
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