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Clinical implications of antitelomeric drugs with respect to the nontelomeric functions of telomerase in cancer

Telomerase is responsible for maintaining the length of telomeres at the ends of chromosomes. Although most somatic cells do not exhibit telomerase activity, it is reactivated in approximately 85% of cancers. This simple and attractive phenomenon steers the development of anticancer drugs targeting...

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Bibliografski detalji
Glavni autori: Roh, Jae-il, Sung, Young Hoon, Lee, Han-Woong
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762763/
https://ncbi.nlm.nih.gov/pubmed/24009427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S50918
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