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MutS Homologue hMSH5: Recombinational DSB Repair and Non-Synonymous Polymorphic Variants

Double-strand breaks (DSBs) constitute the most deleterious form of DNA lesions that can lead to genome alterations and cell death, and the vast majority of DSBs arise pathologically in response to DNA damaging agents such as ionizing radiation (IR) and chemotherapeutic agents. Recent studies have i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Xiling, Xu, Yang, Feng, Katey, Tompkins, Joshua D., Her, Chengtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762724/
https://ncbi.nlm.nih.gov/pubmed/24023853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073284
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