Protein Kinase Cβ Is Required for Lupus Development in Sle Mice

OBJECTIVE: To evaluate the requirement for protein kinase Cβ (PKCβ) in the development of lupus in mice, and to explore the potential of targeting PKCβ as a therapeutic strategy in lupus. METHODS: Congenic mice bearing the disease loci Sle1 or Sle1 and Sle3, which represent different stages of sever...

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Hlavní autoři: Oleksyn, David, Pulvino, Mary, Zhao, Jiyong, Misra, Ravi, Vosoughi, Aram, Jenks, Scott, Tipton, Christopher, Lund, Frances, Schwartz, George, Goldman, Bruce, Mohan, Chandra, Mehta, Kamal, Mehta, Madhu, Leitgets, Michael, Sanz, Ignacio, Chen, Luojing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762702/
https://ncbi.nlm.nih.gov/pubmed/23280626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37825
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