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Proteasomal regulation of caspase-8 in cancer cell apoptosis

Previous studies demonstrated that proteasome inhibition sensitizes TRAIL resistant prostate cancer cells to TRAIL-mediated apoptosis via stabilization of the active p18 subunit of caspase-8. The present study investigated the impact of proteasome inhibition on caspase-8 stability, ubiquitination, t...

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Bibliografiske detaljer
Main Authors: Fiandalo, Michael V., Schwarze, Steven R., Kyprianou, Natasha
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762601/
https://ncbi.nlm.nih.gov/pubmed/23456622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0821-y
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