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A non-stop S-antigen gene mutation is associated with late onset hereditary retinal degeneration in dogs

PURPOSE: To identify the causative mutation of canine progressive retinal atrophy (PRA) segregating as an adult onset autosomal recessive disorder in the Basenji breed of dog. METHODS: Basenji dogs were ascertained for the PRA phenotype by clinical ophthalmoscopic examination. Blood samples from six...

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Autors principals: Goldstein, Orly, Jordan, Julie Ann, Aguirre, Gustavo D., Acland, Gregory M.
Format: Artigo
Idioma:Inglês
Publicat: Molecular Vision 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762564/
https://ncbi.nlm.nih.gov/pubmed/24019744
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