Isoniazid, Rifampin, Ethambutol and Pyrazinamide Pharmacokinetics and Treatment Outcomes among a Predominantly HIV-Infected Cohort of Adults with Tuberculosis — Botswana

BACKGROUND: We explored the association between anti-tuberculosis drug pharmacokinetics and treatment outcomes among pulmonary tuberculosis (TB) patients in Botswana. METHODS: Consenting TB outpatients had blood collected 1, 2, and 6 hours after simultaneous isoniazid, rifampin, ethambutol, and pyra...

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Autori principali: Chideya, Sekai, Winston, Carla A., Peloquin, Charles A., Bradford, William Z., Hopewell, Philip C., Wells, Charles D., Reingold, Arthur L., Kenyon, Thomas A., Moeti, Themba L., Tappero, Jordan W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762461/
https://ncbi.nlm.nih.gov/pubmed/19432554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/599040
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