Using Ion Mobility Spectrometry–Mass Spectrometry to Decipher the Conformational and Assembly Characteristics of the Hepatitis B Capsid Protein

The structural and functional analysis of the core protein of hepatitis B virus is important for a full understanding of the viral life cycle and the development of novel therapeutic agents. The majority of the core protein (CP149) comprises the capsid assembly domain, and the C-terminal region (res...

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Detalhes bibliográficos
Main Authors: Shepherd, Dale A., Holmes, Kris, Rowlands, David J., Stonehouse, Nicola J., Ashcroft, Alison E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762345/
https://ncbi.nlm.nih.gov/pubmed/24010669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.028
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